The Glock 22 is a pistol manufactured by Glock. It is a Glock 17 modified to fire .40 S&W ammunition. It uses a modified slide, frame, .40 S&W barrel and magazine but is otherwise near identical in looks to the Glock 17. It has a 10, 15, or 17 round magazine capacity. One notable feature of the Glock 22, and indeed many modern .40 S&W pistols, is the ability to change the caliber to .357 Sig with a simple barrel swap. This is possible due to the similar operating pressures of both rounds, and the fact that the .357 Sig is based on a .40 S&W case, necked down to accept .355 inch bullets.
Hank Schrader shows off his issue Glock 22 during the party in the Pilot. He actually refers to it as a Glock 22 and praises the power of the .40-caliber round over 9x19mm (claiming to have seen the latter cartridge ricochet off a car windshield).
Hank carries the Glock 22 in One Minute, but he is forced to turn it in along with his badge.