The Colt Woodsman is a semi-automatic sporting pistol. It had a caliber of .22 LR and had a capacity of a 10-round magazine. The .22 caliber Colt automatic pistol, had a bullet weighing only 40 grains and with a striking energy of 51 foot pounds at 25 feet from the muzzle. It is considered to be one of the smallest caliber pistol cartridge made; but also one of the most accurate pistols.
After breaking into his parents' house, Jesse steals a Colt Woodsman and a Smith & Wesson Safety Hammerless from their safe to confront Neil Kandy and Casey with. Upon seeing the Woodsman which Jesse carries in the front of his pants, Neil mocks the .22 in comparison to his .45. Jesse tells Neil he thinks the gun belonged to his grandfather. Neil challenges Jesse to an Old West-style duel for their shares of Todd Alquist's drug money which Jesse accepts. As Neil goes for his gun, Jesse reaches for the Woodsman as a distraction before killing Neil with the Ruger hidden in his jacket pocket. With Casey shooting at him, Jesse ineffectually returns fire with the Woodsman before dropping it in favor of Neil's gun.